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Uptodate Reference Title
Clinical criteria for diagnosis of anaphylaxis
Clinical criteria for diagnosis of anaphylaxis
Clinical criteria for the diagnosis of anaphylaxis:
The clinical criteria pictured are based upon Sampson HA, Munoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: Summary report: Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium. J Allergy Clin Immunol 2006; 117:391.
Anaphylaxis with involvement of only one body organ system and anaphylaxis in infants and young children are described in Simons FER, Ardusso LRF, Bilo MB, et al. World Allergy Organization guidelines for the assessment and management of anaphylaxis. J Allergy Clin Immunol 2011; 127:587.
BP: blood pressure. * For example, immunologic but immunoglobulin E-independent or nonimmunologic (direct mast cell activation). ¶ For example, after an insect sting, reduced BP might be the only manifestation of anaphylaxis or after allergen immunotherapy, generalized hives might be the only initial manifestation of anaphylaxis. Δ Low systolic BP for children is defined as less than 70 mmHg from 1 month to 1 year, less than (70 mmHg + [2 × age]) from 1 to 10 years, and less than 90 mmHg from 11 to 17 years. Normal heart rate ranges from 80 to 140 beats/minute at age 1 to 2 years, from 80 to 120 beats/minute at age 3 years, and from 70 to 115 beats/minute after age 3 years. In infants and children, respiratory compromise is more likely than hypotension or shock, and shock is more likely to be manifested initially by tachycardia than by hypotension.
