Your activity: 230 p.v.
    XAvoid combination
    CMonitor therapy
    ANo known interaction
    DConsider therapy modification
    BNo action needed
        • XAvoid Combination
          Data demonstrate that the specified agents may interact with each other in a clinically significant manner. The risks associated with concomitant use of these agents usually outweigh the benefits. These agents are generally considered contraindicated.
        • DConsider Therapy Modification
          Data demonstrate that the two medications may interact with each other in a clinically significant manner. A patient-specific assessment must be conducted to determine whether the benefits of concomitant therapy outweigh the risks. Specific actions must be taken in order to realize the benefits and/or minimize the toxicity resulting from concomitant use of the agents. These actions may include aggressive monitoring, empiric dosage changes, choosing alternative agents.
        • CMonitor Therapy
          Data demonstrate that the specified agents may interact with each other in a clinically significant manner. The benefits of concomitant use of these two medications usually outweigh the risks. An appropriate monitoring plan should be implemented to identify potential negative effects. Dosage adjustments of one or both agents may be needed in a minority of patients.
        • BNo Action Needed
          Data demonstrate that the specified agents may interact with each other, but there is little to no evidence of clinical concern resulting from their concomitant use.
        • ANo Known Interaction
          Data have not demonstrated either pharmacodynamic or pharmacokinetic interactions between the specified agents
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