| Classic (EDS I, EDS II) | |
| Skin | Velvety or "doughy" texture Stretchy Fragile, easily injured, slow to heal Wide scars from past cuts or injuries |
| Joints | Loose, flexible |
| Other | Fatigue Hernias (weak spots in organ walls that can cause a lump or bulge) Heart problems Soft lumps on the elbows or knees Small bumps on the sides of the feet Pregnancy-related problems |
| Hypermobility (EDS III) | |
| Skin | Soft, smooth, mildly stretchy Not usually fragile |
| Joints | Loose, flexible (including the spine) Frequent dislocations (popping out of place) Chronic pain in the joints |
| Other | Heart problems Digestive problems Fatigue Dizziness upon standing |
| Vascular (EDS IV) | |
| Skin | Thin, bruises easily |
| Joints | Large joints (elbows, knees) usually normal Small joints (fingers, toes) might be somewhat loose or flexible |
| Other | A tear in a blood vessel or organ wall – this can cause internal bleeding and be life threatening Pregnancy-related problems |
