Your activity: 8 p.v.

Categories of abnormal glucose tolerance in cystic fibrosis

Categories of abnormal glucose tolerance in cystic fibrosis
Category Fasting plasma glucose before test Plasma glucose 2 hours after ingestion of 1.75 g/kg glucose Clinical outcomes
Normal glucose tolerance (NGT)

<100 mg/dL

(5.6 mmol/L)

<140 mg/dL

(7.8 mmol/L)
In general, clinically stable
Indeterminate glycemia (INDET)

<100 mg/dL

(5.6 mmol/L)
<140 mg/dL (7.8 mmol/L), with a mid-point peak >200 mg/dL (11.1 mmol/L) Clinical impact unclear but evidence suggests increased risk of morbidity
Impaired glucose tolerance (IGT)

<100 mg/dL

(5.6 mmol/L)

140 to 200 mg/dL

(7.8 to 11.1 mmol/L)
CFRD without fasting hyperglycemia

<126 mg/dL

(7 mmol/L)

≥200 mg/dL

(11.1 mmol/L)
Increased morbidity and mortality
CFRD with fasting hyperglycemia

≥126 mg/dL

(7 mmol/L)
OGTT not necessary
CFRD: cystic fibrosis-related diabetes; OGTT: oral glucose tolerance test.
Modified from: Moran A, Hardin D, Rodman D, Allen HF, Beall RJ, Borowitz D, et al. Diagnosis, screening and management of cystic fibrosis related diabetes mellitus: a consensus conference report. Diabetes Research Clin Practice 1999; 45:61.
Graphic 97528 Version 2.0