Ages at symptom onset for all affected individuals are shown grouped by the affected gene, with APP mutations having an additional subclass for gene duplications.
From: Ryman D, Acosta-Baena N, Aisen P, et al. Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis. Neurology 2014; 83:253. DOI:
10.1212/WNL.0000000000000596. Reproduced with permission from Lippincott Williams & Wilkins. Copyright © 2014 American Academy of Neurology. Unauthorized reproduction of this material is prohibited.
