| Parameters | Transient elastography | pARFI | 2D-SWE | MR elastography | Serum biomarkers |
| Advantages | High accuracy, rapid results | High accuracy, rapid results | High accuracy, rapid results | High accuracy | Availability |
| Reproducibility | Reproducibility | Reproducibility | Reproducibility | Reproducibility | |
| Very easy to learn | Easy to learn | Easy to learn, larger measurement area than other ultrasound techniques | Examination of the whole liver | ||
| Conventional ultrasound images are also obtained | Conventional ultrasound images are also obtained | Conventional MR images are also obtained | |||
| Obesity and ascites are not limiting | Ascites is not limiting | Obesity and ascites are not limiting | |||
| Disadvantages | Technical requirements (elastography equipment) | Technical requirements (ultrasound equipment) | Technical requirements (ultrasound equipment) | Technical requirements (MR imaging equipment) | Nonspecific (eg, hyperbilirubinemia, hemolysis, inflammation) |
| Intermediate cost | Intermediate cost | Intermediate cost | High cost, time-consuming | Relatively high cost, limited availability (patent) | |
| Limited recognition of intermediate stages of fibrosis | Limited recognition of intermediate stages of fibrosis | Limited recognition of intermediate stages of fibrosis | Limited recognition of intermediate stages of fibrosis | Limited recognition of intermediate stages of fibrosis | |
| Blind selection of measurement area | Not applicable in case of iron deposition | Results not immediately available | |||
| Restricted value in obese patients and patients with ascites | Narrow range of values, small measurement area | ||||
| False positive values in patients with acute hepatitis, cholestasis, and heart failure | Quality criteria not well-defined | Quality criteria not well-defined |
