Colitis associated with checkpoint inhibition

(A) Colonoscopic view of bowel edema and ulceration in the descending colon of patient 29, who experienced autoimmune colitis.
(B) Histopathologic analyses revealed focal active colitis (left panel) with crypt destruction, loss of goblet cells, and neutrophilic infiltrates in the crypt epithelium (right panel) (original magnification: left panel, ×20; right panel, ×60).