| Evaluation for uremia |
| Intractable nausea/vomiting with inability to take medications or liquids by mouth |
| Intractable itching |
| Bleeding from gums or other mucosal surfaces |
| Confusion not attributable to other known causes |
| Other symptoms of uremia |
| Evaluation for volume overload |
| Edema of legs above the level of the knee |
| Shortness of breath at rest or dyspnea on minimal exertion (without another readily identifiable cause [ie, COPD, asthma, severe anemia, angina]) |
| Evaluation of laboratory parameters |
| BUN >100 mg/dL |
| Potassium >6.5 mEq/L |
| Bicarbonate <15 mEq/L |
