| Name of tool | Total question number | Domains assessed (number of questions) | Time frame | Comment |
| General health scales |
| EQ-5D (formally EuroQol) | 6 | - Physical function (2): mobility, self-care
- Social functioning (1): usual activities
- Symptom (1): pain/discomfort
- Mental functioning (1): anxiety/depression
- Health state thermometer
| Current | |
| Medical Outcomes Study 36 (MOS SF-36) version 2.0 | 36 | - General health
- Comparison to 1 year ago
- 8 scales/domains: physical functioning, role limitations due to physical issues, bodily pain, general health, vitality, social functioning, role limitations due to emotional problems, mental health
- 2 summary measures that aggregate scales
| Past 4 weeks | Healthy and ill individuals Available in standard (4-week) and acute (1-week) recall versions |
| Sickness Impact Profile (SIP) | 136 | - 2 domains: physical, psychosocial
- 12 categories: sleep/rest, eating, work, home management, recreation, ambulation, mobility, body care and movement, social interaction, alertness, emotional functioning, communication
| Current | For individuals with chronic illness Shorter version (68 items) also available |
| Disease-specific QOL scales (for patients with cancer) |
| European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30) version 3.0 | 30 | - Global health (2)
- Functional Scales
- Physical functioning (5)
- Role functioning (2)
- Emotional functioning (4)
- Cognitive functioning (2)
- Social functioning (2)
- Symptoms scales/items
- Fatigue (3)
- Nausea/vomiting (2)
- Pain (2)
- Global QOL (1 each: dyspnea, insomnia, appetite, constipation, diarrhea, financial)
| Past week | Any cancer |
| Functional Assessment of Cancer Therapy-General (FACT-G) version 4 | 27 | - 4 domains/scales: functional wellbeing, emotional wellbeing, social/family wellbeing, physical wellbeing
| Past week | Any cancer |
| Site-specific symptom and functional assessment tools |
| EORTC QLQ-H&N35 | 35 | - 7 domains/scales: pain (4), swallowing (4), senses (2), speech (3), social eating (4), social contact (5), sexuality (2)
- Single items specific to HNC: teeth, trismus, dry mouth, sticky saliva, cough, felt ill, pain killers, nutritional supplements, feeding tube, weight loss, weight gain
| Past week | HNC Designed to be used with EORTC-C30 |
| FACT-H&N (version 4) | 39 | - Physical wellbeing (7)
- Social/family wellbeing (7)
- Emotional wellbeing (6)
- Functional wellbeing (7)
- H&N specific (12)
| Past week | HNC Not tested as thoroughly as FACT-G |
| University of Washington UW-QOL | 16 | - Global health (3)
- Symptoms (pain, appearance, swallowing, chewing, speech, shoulder, taste, saliva)
- Function (activity, recreation, mood, anxiety)
| Past week | HNC |
| VHNSS version 2.0 | 50 | - Nutrition (4)
- Swallowing/eating foods (9)
- Xerostomia (4)
- Mucositis (3)
- Pain (4)
- Excess mucus (4)
- Speech/communication (3)
- Hearing (1)
- Taste Change (4)
- Smell (2)
- Dental health (5)
- Mucosal sensitivity (5)
- Range of motion (2)
| Past week | HNC |
| MD Anderson Symptom Inventory (MDASI)-HN | 28 | - 13 general symptom severity items: pain, fatigue, nausea, sleep, distress, shortness of breath, appetite, drowsiness, dry mouth, sadness, vomiting, memory, numbness or tingling
- 6 general symptom interference items: general activity, mood, walking ability, normal work, relationships, enjoyment of life
- 9 HNC treatment related: mucus, swallowing/chewing, choking/coughing, voice/speech, skin, constipation, taste, oral sores, dental health
| Current | HNC |
