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Algorithm for monitoring disease response to initial therapy in chronic myeloid leukemia (CML)

This algorithm provides an approach to monitoring patients with CML. Cytogenetics are the preferred method for assessment until a complete cytogenetic response is attained.

CML: chronic myeloid leukemia; PCR: polymerase chain reaction; Ph: Philadelphia chromosome; Ph+: Philadelphia chromosome positive; RT-PCR: reverse transcription polymerase chain reaction; CHR: complete hematologic response.

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