| 1. Pattern of fatigue | Onset, duration, change over time, relationship to treatment |
| 2. Description of fatigue in patient's own words and intensity | Use a valid tool for assessing intensity of fatigue-that is, the Brief Fatigue Inventory |
| 3. Factors that alleviate or aggregate fatigue | Disease status, treatment history, treatment-related symptoms Sleep or rest patterns, relaxation habits Current medications, including alcohol and other risk substances Possible stressors (for example, life events: recent bereavement or loss; change in home setting, financial resources, or support systems) Nutrition intake and any appetite or weight changes, muscle wasting Level of activity or exercise |
| 4. Effects of fatigue on daily living and lifestyle | Determine the activities with which fatigue interferes; impact on work, participation in social life, and other leisure activities; work; concentration; short-term memory |
| 5. Possible contributing factors | Consider anemia, depression, anxiety, pain, dehydration, nutritional deficiencies (for example, protein, calories, vitamins), sedating medications (for example, opioids, benzodiazepines), neurotoxic therapies, infection, fever, sleep disturbances, inactivity, or other symptoms ( for example, dyspnea) |
| 6. Physical exam | Check for signs of nutritional deficiencies, gait and posture, muscle wasting |
