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Uptodate Reference Title
Diagnostic algorithm for suspected inflammatory brain diseases in children
Diagnostic algorithm for suspected inflammatory brain diseases in children
Diagnostic algorithm for suspected inflammatory brain diseases in children. All patients need an initial evaluation, including laboratory tests and MRI or angiography. If initial evaluation does not reveal a definitive diagnosis, a targeted evaluation should be performed. Patients not diagnosed after the targeted evaluations require a brain biopsy to confirm diagnosis.
CNS: central nervous system; CRP: C‑reactive protein; ESR: erythrocyte sedimentation rate; vWF: von Willebrand factor; CBC: complete blood count; IgG: immunoglobulin G; MRI: magnetic resonance imaging; FLAIR: fluid-attenuated inversion recovery; DWI: diffusion-weighted imaging; ADC: apparent diffusion coefficients; PACNS: primary angiitis of the central nervous system; NMO: neuromyelitis optica; CSF: cerebrospinal fluid.
