Catch-up schedule for Haemophilus influenzae type b (Hib) immunization for children (<5 years) in the United States who are not at high-risk of invasive Hib disease

Catch-up schedule for Haemophilus influenzae type b (Hib) immunization for children (<5 years) in the United States who are not at high-risk of invasive Hib disease

Current age	Catch-up regimen
<6 months	Up to three doses of PRP-T* or two doses of PRP-OMP ≥4 weeks apart before age 12 months and one dose of Hib conjugate vaccine at 12 through 15 months of age at least 8 weeks after the previous dose
7 through 11 months	Up to two doses of PRP-T* or PRP-OMP ≥4 weeks apart before age 12 months and one dose of Hib conjugate vaccine at 12 through 60 months of age at least 8 weeks after the previous dose
12 through 14 months	Two doses of Hib conjugate vaccine ≥8 weeks apart, up to 60 months of age
15 through 59 months	Single dose of Hib conjugate vaccine up to 60 months of age

PRP-T: polyribosylribitol phosphate conjugated to tetanus toxoid; PRP-OMP: polyribosylribitol phosphate conjugated to the outer membrane protein complex of Neisseria meningitides; DTaP: diphtheria tetanus-toxoid-acellular pertussis vaccine; IPV: inactivated polio vaccine.
* PRP-T Hib conjugate vaccines approved for this age group include ActHIB, Hiberix, and DTaP-IPV/Hib.

Data from:

Briere EC, Rubin L, Moro PL, et al. Prevention and control of Haemophilus influenzae type b Disease: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2014; 63:1.
Centers for Disease Control and Prevention. Catch-up immunization schedule for children and adolescents who start late or who are more than 1 month behind. Recommendations for ages 18 years or younger, United States, 2022. Available at: www.cdc.gov/vaccines/schedules/hcp/imz/catchup.html. Accessed on February 21, 2022.

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