Calculator: Clinical characteristics comprising the HAS-BLED bleeding risk score in adults

		Hypertension (1 point)
		Abnormal liver function (1 point)
		Abnormal renal function (1 point)
		Stroke (1 point)
		Bleeding tendency or predisposition (1 point)
		Labile INRs in patients taking warfarin (1 point)
		Elderly: age greater than 65 years (1 point)
		Drugs: concomitant antiplatelet agents (eg, aspirin, clopidogrel, ticlopidine, nonsteroidal antiinflammatory agents) (1 point)
		Drugs: concomitant excess alcohol use (1 point)

Important: Inputs must be complete to perform calculation.

Total criteria point count:

HAS-BLED score interpretation

0 points:	1.13 bleeds per 100 patient-years
1 point:	1.02 bleeds per 100 patient-years
2 points:	1.88 bleeds per 100 patient-years
3 points:	3.74 bleeds per 100 patient-years
4 points:	8.70 bleeds per 100 patient-years
5 to 9 points:	Insufficient data

Notes

Abnormal liver function: Chronic liver disease (eg, cirrhosis) or biochemical evidence of significantly impaired liver function (eg, bilirubin >2 times ULN plus one or more liver enzymes >3 times ULN)
Abnormal renal function: Chronic dialysis, renal transplantation, or serum creatinine ≥2.26 mg/dL (200 micromol/L)
Stroke: Previous history
Bleeding: Bleeding disorder or previous bleeding episode requiring hospitalization or transfusion
Labile INRs: Unstable/high INRs or <60 percent of INR values in therapeutic range
INR: international normalized ratio; ULN: upper limit of normal

References

Lip GY. Implications of the CHA(2)DS(2)-VASc and HAS-BLED Scores for thromboprophylaxis in atrial fibrillation. Am J Med 2011; 124:111.

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All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.

Topic 94104 Version 6.0