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Estimated electrolyte content of cholera stool and therapeutic fluids for cholera

Estimated electrolyte content of cholera stool and therapeutic fluids for cholera
  Millimoles/liter Comment
Na+ K+ Cl– HCO3– Carbohydrate
Electrolyte losses in stools
Cholera stool, adult 130 20 100 45 -- Stool sodium losses in cholera are higher than in other diarrheal illnesses.
Cholera stool, child 100 30 90 30 --
Non-cholera stool, child (ETEC) 50 35 25 20 --
Intravenous therapy
Lactated Ringer's solution 130 4 109 28 -- Lactated Ringer's (LR) solution is preferred over normal saline because it contains potassium and bicarbonate. 'Dhaka solution' contains more potassium and bicarbonate than LR, and also contains dextrose.
Normal saline 154 0 154 0 --
Cholera saline (Dhaka solution) 133 13 154 48 140
Oral rehydration therapy
ORS (WHO 2002) 75 20 65 10 (citrate) 75 (glucose) WHO ORS utilizes glucose as a carbohydrate source. Rice based ORS formulation have been found in randomized trials to reduce the duration of diarrhea and stool losses in severe cholera. A homemade preparation of ORS could be used in an emergency scenario.
Rice based ORS (eg, CeraORS 75®) 75 20 65 10 (citrate) 27 grams rice syrup solids
Homemade ORS:
  • Half (1/2) teaspoon salt
  • Six (6) teaspoons sugar
  • 1 liter of clean water
~75 0 ~75 0 ~75
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