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Pediatric donor management goals

Pediatric donor management goals
Hemodynamic support   Blood pressure (mmHg)
Systolic* Diastolic
  • Normalization of blood pressure
    • Systolic blood pressure appropriate for age
    • NOTE: Lower systolic blood pressures may be acceptable if biomarkers such as lactate are normal
  • CVP <12 (if measured)
  • Dopamine <10 mcg/kg/min
  • Normal serum lactate
Neonate 60-90 35-60
Infants
(6 months)
80-95 50-65
Toddler
(2 years)
85-100 50-65
School age
(7 years)
90-115 60-70
Adolescent
(15 years)
110-130 65-80
Oxygenation and ventilation Fluids and electrolytes
  • Maintain PaO2 >100 mmHg
  • FiO2 0.40
  • Normalize PaCO2 35-45 mmHg
  • Arterial pH 7.30-7.45
  • Tidal volumes 8-10 cc/kg
  • PEEP 5 cm H2O
  • Serum Na+ 130-150 mEq/L
  • Serum K+ 3-5 mEq/L
  • Serum glucose 60-150 mg/dL
  • Ionized Ca++ (if measured) 0.8-1.2 mmol/L
Thermal regulation
Core body temperature 36-38°C
CVP: central venous pressure; PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; FiO2: fraction of inspired oxygen; PEEP: positive end-expiratory pressure.
* Normal systolic blood pressure = 80 + (age in years x 2).
Reproduced with permission from: Nakagawa TA. Updated Pediatric donor management guidelines. NATCO, The Organization for Transplant Professionals, 2008. Copyright © 2008 NATCO.
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