Cough: Oral: 100 to 200 mg 3 times/day as needed for cough (maximum single dose: 200 mg; maximum dose: 600 mg/day).
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
(For additional information see "Benzonatate: Pediatric drug information")
Cough: Children >10 years and Adolescents: Oral: 100 to 200 mg 3 times daily as needed for cough; maximum dose: 200 mg/dose; maximum daily dose: 600 mg/day
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Capsule, Oral:
Tessalon Perles: 100 mg [DSC]
Generic: 100 mg, 150 mg, 200 mg
Yes
Oral: Swallow capsule whole (do not break, chew, dissolve, cut, or crush). If capsules are chewed or dissolved in the mouth, oral mucosa anesthesia may occur and could lead to choking. If numbness or tingling of the tongue, mouth, throat, or face occurs, refrain from oral ingestion of food or liquid until numbness has resolved.
Oral: Swallow capsule whole (do not break, chew, dissolve, cut, or crush). If capsules are chewed or dissolved in the mouth, oral mucosa anesthesia may occur and could lead to choking. If numbness or tingling of the tongue, mouth, throat, or face occurs, refrain from oral ingestion of food or liquid until numbness has resolved.
Cough: Symptomatic relief of cough
The following adverse drug reactions are derived from product labeling unless otherwise specified.
Postmarketing:
Cardiovascular: Chest numbness
Dermatologic: Pruritus, skin rash
Gastrointestinal: Constipation, gastrointestinal distress, nausea (Bishop-Freeman 2017)
Hypersensitivity: Hypersensitivity reaction (including severe hypersensitivity reaction)
Nervous system: Chills, confusion, dizziness (Bishop-Freeman 2017), drowsiness (Bishop-Freeman 2017), hallucination, headache (Bishop-Freeman 2017), numbness of tongue (Bishop-Freeman 2017), sedated state (Bishop-Freeman 2017)
Ophthalmic: Burning sensation of eyes
Respiratory: Nasal congestion
Hypersensitivity to benzonatate, related compounds, or any component of the formulation
Concerns related to adverse effects:
• Hypersensitivity reactions: Severe hypersensitivity reactions, including bronchospasm, cardiovascular collapse and laryngospasm have been reported. May be related to localized anesthetic effects due to sucking or chewing the capsule instead of swallowing it.
• Psychiatric effects: Isolated cases of bizarre behavior, including mental confusion and visual hallucinations have been reported during concurrent use with other prescribed drugs.
Special populations:
• Pediatric: Accidental ingestion and potentially fatal overdose of benzonatate has been reported in children <10 years of age. Signs and symptoms of overdose (restlessness, tremors, convulsion, coma, cardiac arrest) may occur within 15 to 20 minutes and death has been reported within 1 hour of ingestion. Not approved for use in children <10 years of age.
None known.
There are no known significant interactions.
Animal reproduction studies have not been conducted. Information related to use in pregnancy is limited (Heinonen 1977).
It is not known if benzonatate is present in breast milk. The manufacturer recommends that caution be exercised when administering benzonatate to breastfeeding women.
Tetracaine congener with antitussive properties; suppresses cough by topical anesthetic action on the respiratory stretch receptors
Onset of action: Therapeutic: 15 to 20 minutes
Duration: 3 to 8 hours
Capsules (Benzonatate Oral)
100 mg (per each): $0.12 - $2.50
150 mg (per each): $2.12 - $2.64
200 mg (per each): $0.21 - $4.77
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