| Preservative | NACDG 2015 to 2016 reactions (percent) |
| Methylisothiazolinone | 13.4 |
| Formaldehyde | 8.4 |
| MCI/MI | 7.3 |
| Iodopropynyl butylcarbamate | 3.9 |
| Quaternium 15 | 3.6 |
| Methyldibromo glutaronitrile | 3.5 |
| 2-bromo-2-nitropropane-1,3-diol | 1.3 |
| Diazolidinyl urea | 1.2 |
| Imidazolidinyl urea | 1.1 |
| DMDM hydantoin | 0.8 |
| Parabens | 0.6 |
