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Diseases associated with a positive ANA

Diseases associated with a positive ANA
  Percent with positive ANA
Systemic autoimmune diseases
SLE
Active 98 to 100 percent
Remission 90 percent
Scleroderma 95 percent
Rheumatoid arthritis 45 percent
Sjögren's syndrome 60 percent
Mixed connective tissue disease 100 percent
Drug-induced LE 80 to 95 percent
Raynaud's phenomenon 40 percent
Polymyositis/dermatomyositis 35 percent
Juvenile idiopathic arthritis 15 to 40 percent
Organ-specific autoimmune diseases
Hashimotos thyroiditis 50 percent
Graves' disease 50 percent
Autoimmune hepatitis 70 percent
Primary biliary cirrhosis 50 to 70 percent
Infectious diseases*
Viral:
EBV
HIV
HCV
Parvovirus 19
Bacterial:
SBE
Syphilis
Malignancies*
Lymphoproliferative diseases
Paraneoplastic syndromes
Miscellaneous diseases*
Inflammatory bowel disease
Interstitial pulmonary fibrosis
ANA: antinuclear antibodies; SLE: systemic lupus erythematosus; EBV: Epstein-Barr virus; HCV: hepatitis C virus; SBE: subacute bacterial endocarditis.
* Although positive tests of ANA are reported in these diseases more often than in healthy controls, precise estimates vary.
Courtesy of Donald B Bloch, MD.
Graphic 89802 Version 2.0