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Infections most commonly seen in patients with common variable immunodeficiency (CVID)

Infections most commonly seen in patients with common variable immunodeficiency (CVID)
Lungs
  • Pneumonia (bacterial, especially encapsulated bacteria/mycoplasma)
  • Bronchiectasis resulting from recurrent infections
  • Acute or chronic bronchitis
Head and neck
  • Rhinosinusitis (bacterial, especially encapsulated bacteria, and viral)
  • Otitis media
  • Conjunctivitis (especially nonencapsulated H. influenzae)
Gastrointestinal tract
  • Acute infectious diarrhea (Norovirus, Campylobacter jejuni, Salmonella)
  • Acute or chronic infections with Giardia lamblia (causing diarrhea, malabsorption, weight loss)
  • Helicobacter pylori
  • Cytomegalovirus
  • Bacterial overgrowth
  • Cryptosporidium
Urinary tract
  • Mycoplasma/ureaplasma species
Joints
  • Septic arthritis (acute monoarthritis or chronic degenerative polyarthritis)
Skin
  • Herpes zoster
  • Molluscum
Central nervous system
  • Meningitis
Systemic
  • Bacterial sepsis, especially encapsulated bacteria
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