Antiseptic (OTC labeling): Oral: Swish 20 mL thoroughly between teeth for 30 seconds then spit; use twice daily; may be used before or after brushing; do not swallow.
Antiseptic (OTC labeling): Children ≥6 years: Refer to adult dosing.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Liquid, Mouth/Throat, as chloride:
Cepacol Antibacterial: 0.05% (710 mL) [contains alcohol, usp, edetate (edta) disodium, fd&c yellow #5 (tartrazine), menthol, polysorbate 80, saccharin sodium]
Clean Zing: 0.06% (480 mL [DSC]) [alcohol free, no artificial color(s); contains sodium benzoate]
GoodSense Oral Rinse: 0.07% (1000 mL) [alcohol free; contains fd&c blue #1 (brilliant blue), methylparaben, propylene glycol, propylparaben, saccharin sodium]
Lozenge, Mouth/Throat, as chloride:
Larynex: (500 ea [DSC])
Yes
Vigorously swish between teeth; do not swallow.
Oral: Vigorously swish between teeth; do not swallow. Supervise use in children 6 to <12 years of age.
Antiseptic to aid in the prevention and reduction of plaque and gingivitis, and to freshen breath
There are no adverse reactions listed in the manufacturer's labeling.
Postmarketing: Hypersensitivity: Type 1 hypersensitivity reaction (Shima 2015)
Hypersensitivity to cetylpyridinium or any component of the formulation
Other warnings/precautions:
• Accidental ingestion: If an amount greater than used for rinsing is swallowed, seek professional assistance or contact a poison control center immediately.
• Self-medication (OTC use): Stop use and consult a healthcare professional if symptoms or condition worsening or persists; if gingivitis, bleeding, or redness persists for more than 2 weeks; if gums are painful and swollen; if pus from the gum line, loose teeth, or increased spacing between the teeth occurs. Avoid contact with eyes.
None known.
There are no known significant interactions.
Cetylpyridinium chloride mouthwash (alcohol free) has been associated with a reduction in preterm births in pregnant women with periodontal disease (Jeffcoat, 2011).
Liquid (Cepacol Antibacterial Mouth/Throat)
0.05% (per mL): $0.01
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