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Short-term and long-term adverse effects of UVB phototherapy

Short-term and long-term adverse effects of UVB phototherapy
Acute
Sunburn or phototoxic reaction if overdosed ++
Phototoxic reaction from accidental intake of a photosensitizer –
Conjunctivitis, keratitis (if no eye shielding is used) ++
Provocation of photodermatoses (eg, polymorphous light eruption) +
Chronic
Lentigines +
Photoaging ++
Actinic keratosis, nonmelanoma skin cancer +/±
Melanoma ?
–: no risk; ++: high risk; +: medium risk; ±: low risk; ?: possible, insufficient data.
Most photosensitizing substances absorb in the UVA range. Thus, exposure to UVB after the accidental ingestion of a photosensitizer does not induce a phototoxic reaction.
Graphic 87496 Version 2.0