| Generic name | Example brand name(s) | How it is usually taken |
| Conventional synthetic DMARDs | ||
| Azathioprine | Imuran, Azasan | Pill |
| Hydroxychloroquine | Plaquenil | Pill |
| Leflunomide | Arava | Pill |
| Methotrexate | Pills: Rheumatrex, Trexall Auto-injectors (these let you give yourself a shot): Otrexup, Rasuvo | Pill or shot under the skin or in a muscle IMPORTANT: Methotrexate is only taken once per week. Always double-check the instructions with your doctor and pharmacist when you get a new prescription. |
| Sulfasalazine | Azulfidine, Azulfidine EN tabs | Pill |
| Biologic DMARDs | ||
| Abatacept | Orencia | Shot under the skin or into a vein (by IV) at a clinic or doctor's office |
| Adalimumab | Humira | Shot under the skin |
| Anakinra | Kineret | Shot under the skin |
| Certolizumab pegol | Cimzia | Shot under the skin |
| Etanercept | Enbrel | Shot under the skin |
| Golimumab | Simponi | Shot under the skin or into a vein (by IV) at a clinic or doctor's office |
| Guselkumab | Tremfya | Shot under the skin |
| Infliximab | Avsol, Inflectra, Remicade, Renflexis | Into a vein (by IV) at a clinic or doctor's office |
| Ixekizumab | Taltz | Shot under the skin |
| Risankizumab | Skyrizi | Shot under the skin |
| Rituximab | Riabni, Rituxan, Ruxience, Truxima | Into a vein (by IV) at a clinic or doctor's office |
| Sarilumab | Kevzara | Shot under the skin |
| Secukinumab | Cosentyx | Shot under the skin |
| Tocilizumab | Actemra | Shot under the skin or into a vein (by IV) at a clinic or doctor's office |
| Ustekinumab | Stelara | Shot under the skin |
| Targeted synthetic DMARDs | ||
| Baricitinib | Olumiant | Pill |
| Tofacitinib | Xeljanz | Pill |
| Upadacitinib | Rinvoq | Pill |
