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Modified NIH risk stratification criteria for GIST with rupture included

Modified NIH risk stratification criteria for GIST with rupture included
Risk category Tumor size (cm) Mitotic index (per 50 HPFs) Primary tumor site
Very low risk <2.0 ≤5 Any
Low risk 2.1 to 5.0 ≤5 Any
Intermediate risk 2.1 to 5.0 >5 Gastric
<5.0 6 to 10 Any
5.1 to 10.0 ≤5 Gastric
High risk Any Any Tumor rupture
>10 cm Any Any
Any >10 Any
>5.0 >5 Any
2.1 to 5.0 >5 Nongastric
5.1 to 10.0 ≤5 Nongastric
NIH: National Institutes of Health; GIST: gastrointestinal stromal tumor; HPF: high power fields.
Reproduced from: Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol 2008; 39:1411. Table used with the permission of Elsevier Inc. All rights reserved.
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