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Features associated with, or contributing to, appearance of central apneas in treatment-emergent central sleep apnea

Features associated with, or contributing to, appearance of central apneas in treatment-emergent central sleep apnea
Non-rapid eye movement (NREM) sleep
Severe OSA
Supine position
Higher CPAP levels ("over-titration")
Higher pressure support level
Altitude
Oral breathing
Opioid narcotics
Congestive heart failure
OSA: obstructive sleep apnea; CPAP: continuous positive airway pressure.
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