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Peripheral blood cytometric analysis in ALPS

Peripheral blood cytometric analysis in ALPS
Typically <1% of TCR-alpha-beta+ T cells do not express CD4 or CD8. In ALPS, this population is greatly increased (top panels). In addition, these cells express B220 (bottom panels).
ALPS: autoimmune lymphoproliferative syndrome; TCR: T cell receptor.
Graphic 82246 Version 3.0