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Probability of thromboembolism in pregnant women with inherited thrombophilias

Probability of thromboembolism in pregnant women with inherited thrombophilias
Lesion Prevalence if no history of thrombosis, percent Probability of thrombosis per pregnancy in carriers, percent
Factor V Leiden 7.7 0.25
Prothrombin gene mutation 1.3 0.5
Both factor V Leiden and prothrombin gene mutation 0.1 4.6
Antithrombin (ATIII) deficiency 1.5 0.4
Protein C deficiency 3.3 0.1
Protein S deficiency 6.6  
No abnormality   0.03
Probability_of_thromboembol.htm
Data from Gerhardt, AG, Scharf, RE, Beckmann, MW, et al, N Engl J Med 2000: 342:374.
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