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Progressive obesity in Cushing's syndrome

Progressive obesity in Cushing's syndrome
Sequence of pictures in a boy with Cushing's disease.
(A) Age six years, before apparent onset of Cushing's syndrome.
(B) Age seven years, still with little evidence of cushingoid appearance.
(C) Age eight years, with early facial rounding.
(D) Age nine years, with "moon" facies.
(E) Age 11 years, with florid Cushing's disease.
Reproduced with permission from Williams Textbook of Endocrinology, 8th ed, Foster DW, Wilson JD (Eds), WB Saunders, Philadelphia, 1996.
Graphic 82114 Version 3.0