Laparoscopic ovarian drilling | Gonadotropin ovulation induction | |
Advantages | One-time, minimally invasive procedure Normalizes endocrinologic and ultrasonographic abnormalities Restores ovulatory cycles for many years Pregnancy and live birth rates are comparable to gonadotropin ovulation induction with no increase in multiple pregnancy or OHSS Improves response to gonadotropin superovulation for IVF May improve acne and hirsutism | Comparable pregnancy and live birth rates to ovarian drilling without surgery Widespread availability |
Disadvantages | Surgical risks inherent with laparoscopy Postoperative adhesions Diminished ovarian reserve versus normalization of elevated AMH and antral follicle counts Few clinicians in the United States offer it | Significantly higher risk for multiple pregnancy Higher risk of OHSS Greater cost compared with ovarian drilling High patient inconvenience due to daily injections and frequent visits for monitoring No benefit beyond the treatment cycle |