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Endothelin system in vascular tissue
Endothelin system in vascular tissue
ET: endothelin-1; BIG-ET-1: proendothelin-1; ECE: endothelin-converting enzyme; NO: nitric oxide; PGI
2
: prostacyclin.
Reproduced with permission from: Dupuis, J. Endothelin-receptor antagonists in pulmonary hypertension. Lancet 2001; 358:1114. Copyright © 2001, The Lancet Ltd.
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