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Clinical features of opioid withdrawal

Clinical features of opioid withdrawal
Vital signs
Blood pressure increased or unchanged; decreased if hypovolemic
Heart rate increased or unchanged
Respiratory rate increased or unchanged
Temperature unchanged
Gastrointestinal
Nausea, vomiting
Diarrhea, increased bowel sounds
Neurological
Mental status usually normal, irritable
Restlessness
Seizures (neonates only)
Tremor
Yawning
Ophthalmologic
Lacrimation
Mydriasis
Skin
Piloerection
Diaphoresis
Other findings
Rhinorrhea 
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