Lumbar spine bone mineral density, mean percentage change from baseline (± SEM)
Lumbar spine bone mineral density, mean percentage change from baseline (± SEM)
Number of participants with at least one post-baseline evaluation for placebo, 100, 200, and 400 IU; n = 268, 273, 280, and 274, respectively. A single asterisk indicates p<0.05 versus placebo; a double asterisk indicates p<0.01 versus placebo.
IU: international units; SEM: standard error of the mean.
Data from: Chesnut CH, Silverman S, Andriano K, et al. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the Prevent Recurrence of Osteoporotic Fractures Study. Am J Med 2000; 109:267.
