| Situation | Associated neurotransmitters | Recommended antiemetic |
| Migraine headache | Dopamine (probably a primary mediator) | For headache and nausea: metoclopramide or prochlorperazine |
| For nausea: oral antiemetics, metoclopramide, prochlorperazine, serotonin antagonists | ||
| Vestibular nausea | Histamine, acetylcholine | Antihistamines and anticholinergics (equally effective) |
| Pregnancy-induced nausea | Unknown | For nausea: ginger, vitamin B6 |
| For hyperemesis gravidarum: promethazine (first-line agent); serotonin antagonists and corticosteroids (second-line agents) | ||
| Gastroenteritis | Dopamine, serotonin | First-line agents: dopamine antagonists |
| Second-line agents: serotonin antagonists | ||
| Use in children is controversial | ||
| Postoperative nausea and vomiting | Dopamine, serotonin | Prevention: serotonin antagonists, droperidol, dexamethasone |
| Treatment: dopamine antagonists, serotonin antagonists, dexamethasone |
