Interval After Exposure | |||
Case 1 | |||
60 hours | 15 days | 60 days | 150 days |
Superficial fibrinohemorrhagic layer replacing bronchial epithelium that has sloughed | Persistence of hemorrhage, bronchial epithelium sloughing; increased deposition of collagen | Regeneration of epithelial cells (basal); collagen deposition; spots of lymphocytes; few PMNs; increase in thickness of basement membrane | Complete regeneration of the epithelium layer; numerous basal cells indicating regeneration. |
Case 2 | |||
45 days | 98 days | ||
Severe damage of the epithelial layer with few remaining basal cells; subepithelial edema with inflammatory cells underneath the basement membrane. | Incomplete regeneration of the epithelial layer with few ciliated cells; inflammatory cells persisting in epithelium and connective tissue. |