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Time course of histologic lesions of RADS at different intervals after exposure

Time course of histologic lesions of RADS at different intervals after exposure
Interval After Exposure
Case 1
60 hours 15 days 60 days 150 days
Superficial fibrinohemorrhagic layer replacing bronchial epithelium that has sloughed Persistence of hemorrhage, bronchial epithelium sloughing; increased deposition of collagen Regeneration of epithelial cells (basal); collagen deposition; spots of lymphocytes; few PMNs; increase in thickness of basement membrane Complete regeneration of the epithelium layer; numerous basal cells indicating regeneration.
Case 2
45 days  98 days
Severe damage of the epithelial layer with few remaining basal cells; subepithelial edema with inflammatory cells underneath the basement membrane. Incomplete regeneration of the epithelial layer with few ciliated cells; inflammatory cells persisting in epithelium and connective tissue.
Lesions_after_exposure_to_R.htm
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