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Some estrogen products

Some estrogen products
Drug and United States brand name Available strengths
Estrogen preparations and doses for the management of vasomotor symptoms
Oral estradiol*
Estrace 0.5, 1, 2 mg
Oral esterified estrogen*
Menest 0.3, 0.625, 1.25 mg
Oral CEE*
Premarin 0.3, 0.45, 0.625, 0.9, 1.25 mg
Oral estrogen-progestin combinations
PremproΔ 0.3 mg CEE/1.5 mg medroxyprogesterone, 0.45/1.5 mg, 0.625/2.5 mg, 0.625/5 mg
Prefest 1 mg estradiol/0.09 mg norgestimate (cyclic)
Activella, Amabelz, Mimvey 0.5 mg estradiol/0.1 mg norethindrone acetate, 1 mg/0.5 mg
FemHRT, Jevantique Lo 2.5 mcg ethinyl estradiol/0.5 mg norethindrone acetate
Jinteli 5 mcg ethinyl estradiol/1 mg norethindrone acetate
Angeliq 0.5 mg estradiol/0.25 mg drospirenone, 1 mg/0.5 mg
Oral CEEs and bazedoxifene
Duavee 0.45 mg CEE/20 mg bazedoxifene
Estradiol patches*
Alora (twice weekly) 0.025, 0.05, 0.075, 0.1 mg per day
Generic (twice weekly) 0.025, 0.0375, 0.05, 0.075, 0.1 mg per day
Minivelle (twice weekly) 0.025, 0.0375, 0.05, 0.075, 0.1 mg per day
Vivelle-Dot (twice weekly) 0.025, 0.0375, 0.05, 0.075, 0.1 mg per day
Climara (weekly) 0.025, 0.0375, 0.05, 0.06, 0.075, 0.1 mg per day
Menostar (weekly) 0.014 mg per day
Estrogen-progestin patches
Combi-Patch (twice weekly) 0.05 mg estradiol/0.14 mg norethindrone, 0.05 mg/0.25 mg per day
Climara Pro (weekly) 0.045 mg estradiol/0.015 mg levonorgestrel per day
Topical gel*
EstroGel 0.06% 0.75 mg estradiol per pump
Elestrin 0.06% 0.52 mg estradiol per pump
Divigel 0.1% 0.25, 0.5, 1 mg estradiol per pouch
Topical spray*
EvaMist 1.53 mg estradiol per spray
Intravaginal rings*
Femring 0.05 mg estradiol per day over 3 months, 0.1 mg estradiol per day over 3 months
Depot options (oil, intramuscular)
Estradiol cypionate
Depo-Estradiol 5 mg/mL (5 mL)
Estradiol valerate
Delestrogen 10, 20, or 40 mg/mL (all 5 mL)
Vaginal estrogen preparations for treatment of genitourinary atrophy (inadequate dose to relieve vasomotor symptoms)
Vaginal ring
Estring 7.5 mcg estradiol per day, released over 3 months
Vaginal tablet
Vagifem 10 mcg estradiol per vaginal tablet
Yuvafem 10 mcg estradiol per vaginal tablet
Vaginal cream
Estrace 0.01% 0.1 mg estradiol per gram cream
Premarin vaginal 0.625 mg CEE per gram cream
Some esterified estrogen-methyl testosterone (EEMT) combinations remain available in United States. These are considered unapproved products by US Food and Drug Administration (FDA) and are not recommended; refer to section on androgens in UpToDate topic review of treatment of menopausal symptoms with hormone therapy.
CEE: conjugated equine estrogens.
* For women with an intact uterus, a progestin must be added to estrogen therapy.
¶ Also available as a generic product in United States and some other countries.
Δ Also available as Premphase, which contains both combination tablets and estrogen alone.
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