Morphologic features in arrhythmogenic right ventricular cardiomyopathy (ARVC)

Morphologic features in a 25-year-old man who died suddenly from arrhythmogenic right ventricular cardiomyopathy (ARVC).
Panel A: Four chamber view cut of the heart specimen showing the transmural fatty replacement of the right ventricular free wall and the translucent infundibulum.
Panel B: Panoramic histologic view of the same heart confirming that the replacement of the myocardium by fat is largely confined to the right ventricle (arrow) and substantially spares the interventricular septum as well as the left ventricular free wall (trichrome Heidenhain x 3).