Left ventricular mass is an independent predictor of mortality

In the SOLVD trials of 1172 patients with left ventricular (LV) dysfunction, Kaplan-Meier survival curves demonstrate that increased LV mass ≥298 g is an independent risk factor for all-cause mortality (p = 0.0014); a one standard deviation increase in LV mass is associated with a 17 percent increased risk of death. An LV ejection fraction (LVEF) ≥35 percent, however, is protective in those with LV mass ≥298 g.