Prostate tissue immunohistochemistry

Low-power photomicrographs of serial tissue sections of the prostate gland, stained with hematoxylin and eosin (panel A), alpha-methylacyl-CoA racemase (AMACR/P504S) (panel B), and 34bE12 (panel C). The prostate adenocarcinoma stains positively for AMACR (brown stain) and negatively for 34bE12. In contrast, the peripheral benign glands adjacent to the cancer stain negatively for AMACR but positively for 34bE12.