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Arterial calcium stimulation with hepatic venous sampling for insulinoma

Arterial calcium stimulation with hepatic venous sampling for insulinoma
Artery Time, seconds Serum hepatic vein insulin,
microU/mL (pmol/L)
Superior mesenteric 0 41 (284)
20 65 (451)
40 333 (2313)
60 441 (3063)
Gastroduodenal 0 30 (208)
20 42 (292)
40 38 (264)
60 36 (250)
Splenic 0 31 (215)
20 26 (180)
40 26 (180)
60 31 (215)
Intraarterial injection of calcium, an insulin secretagogue in patients with insulinoma but not in healthy individuals, and changes in hepatic venous serum insulin concentrations in a patient with suspected insulinoma. The hepatic venous serum insulin concentration increased 10-fold after superior mesenteric artery injection, 1.4-fold after the gastroduodenal artery injection, and did not change after the splenic artery injection. An insulinoma was removed from the uncinate process.
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