| High-risk conditions |
| Atrial fibrillation associated with valvular heart disease (including the presence of a mechanical valve) |
| Atrial fibrillation associated with congestive heart failure or a left ventricular ejection fraction of <35 percent |
| Atrial fibrillation associated with a history of a thromboembolic event |
| Atrial fibrillation associated with hypertension, diabetes, or age >75 years |
| Mechanical valves in the mitral position |
| Mechanical valves in patients who have had a prior thromboembolic event |
| Coronary stents placed within one year |
| Acute coronary syndrome |
| Nonstented percutaneous coronary intervention after myocardial infarction |
| Low-risk conditions |
| Deep vein thrombosis |
| Chronic or paroxysmal atrial fibrillation that is not associated with valvular disease |
| Bioprosthetic valves |
| Mechanical valves in the aortic position |
