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Uptodate Reference Title
Hypoxia in the renal medulla
Hypoxia in the renal medulla
Development of medullary hypoxia due to the exchange of oxygen between the descending and ascending limbs of the vasa recta capillaries (straight arrows) and to oxygen consumption by the medullary cells (curved arrows). The net effect is that the PO2 falls to 5 to 10 mmHg in the inner medulla.
O2: oxygen; PO2: partial pressure of oxygen.
Modified from:
Brezis M, Rosen S, Silva P, Epstein FH, Kidney Int 1984; 26:375. Reprinted by permission from Kidney International.
Brezis M, Rosen S, Silva P, Epstein FH. Selective anoxic injury to thick ascending limb: an anginal syndrome of the renal medulla? Adv Exp Med Biol 1984; 180:239.