| Vital Signs |
| Heart rate decreased or unchanged |
| Blood pressure decreased or unchanged |
| Respiratory rate decreased |
| Temperature decreased or unchanged |
| Gastrointestinal |
| Decreased bowel sounds |
| Neurological |
| Sedation or coma |
| Seizure (Meperidine, Propoxyphene, Tramadol, or as a result of hypoxia) |
| Ophthalmologic |
| Miosis |
