Skin |
Feeling of warmth, flushing (erythema), itching (may begin on palms and soles), urticaria, angioedema, morbilliform rash, and "hair standing on end" (piloerection) |
Infants and children - Eczematous flare |
Oral |
Itching or tingling of lips, tongue, or palate |
Edema of lips, tongue, uvula, metallic taste |
Infants - Drooling |
Children - Rubbing tongue against pruritic palate, scratching tongue with hand |
Gastrointestinal |
Nausea, abdominal pain (colic, cramps), vomiting (large amounts of "stringy" mucus), and diarrhea |
Difficulty swallowing* |
Respiratory |
Laryngeal - Pruritus and "tightness" in the throat, dysphagia, dysphonia and hoarseness, and sensation of itching in the external auditory canals |
Lung - Shortness of breath, dyspnea, chest tightness, deep or repetitive cough, and wheezing |
Nose - Itching, congestion, rhinorrhea, and sneezing |
Cardiovascular |
Feeling of faintness or dizziness; syncope, chest pain, palpitations, and/or hypotension (tunnel vision, difficulty hearing) |
Neurologic |
Anxiety, apprehension, sense of impending doom, seizures, confusion |
Infants - Lethargy, hypotonia |
Children - Abrupt cessation of activity, fetal position |
Ocular |
Periorbital itching, erythema and edema, tearing, and conjunctival erythema |
Other |
Lower back pain due to uterine cramping in women |
Children - Ear pulling as an indication of pruritus |
Vital signs/other objective measures |
Pulse oximetry, respiratory rate, peak flow, pulmonary function testing |
Pulse, blood pressure |