| Patient and disease characteristics |
| Asymptomatic |
| Chronic condition |
| Condition suppressed, not cured |
| No immediate consequences of stopping therapy |
| Social isolation |
| Disrupted home situation |
| Psychiatric illness |
| Treatment characteristics |
| Long duration of therapy |
| Complicated regimens |
| Expensive medications |
| Side effects of medications |
| Multiple behavioral modifications |
| Lack of specific appointment times |
| Long waiting time in office |
