| Better physical appearance |
| Pubertal growth and sexual development |
| Schooling |
| Working |
| Establishing relationships |
| Getting married |
| Raising a family |
| Low compliance with treatment for large number of patients |
| Living for today |
| Denial/anxiety/hostility |
| Prospects |
| Oral chelators |
| HbF inducers |
| Bone marrow transplantation |
| Gene therapy |
