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Human leukocyte antigen types associated with an increased risk of Stevens-Johnson syndrome/toxic epidermal necrolysis induced by specific drugs
Human leukocyte antigen types associated with an increased risk of Stevens-Johnson syndrome/toxic epidermal necrolysis induced by specific drugs
Drug type yielding increased risk of SJS/TEN
HLA type
Sulfonamides
HLA-A29, HLA-B12, HLA-DR7
Oxicam NSAIDs
HLA-A2, HLA-B12
Carbamazepine
HLA-B*15:02
Allopurinol
HLA-B*58:01
SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis; HLA: human leukocyte antigen; NSAIDs: nonsteroidal anti-inflammatory drugs.
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