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Criteria for pulmonary metastatic disease as used in the EURAMOS I (AOST0331) osteosarcoma trial

Criteria for pulmonary metastatic disease as used in the EURAMOS I (AOST0331) osteosarcoma trial
CT chest finding Interpretation

1 or more pulmonary/pleural nodule(s) ≥1 cm

or

3 or more nodules ≥0.5 cm maximum diameter
"Certain" pulmonary metastases
Fewer or smaller lesions "Possible" metastatic disease
CT: computed tomography.
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