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Muscle characteristics of myotonic dystrophy (DM), types I and II

Muscle characteristics of myotonic dystrophy (DM), types I and II
Type of DM Muscle groups commonly affected Clinical myotonia (grip and percussion)* Muscle pain Respiratory muscle involvementΔ Dysphagia and dysarthriaΔ
DM I (Steinert's disease) Facial, neck, forearm, hand intrinsic, foot dorsiflexor Common and often pronounced Yes (Rarely a presenting complaint) Yes Yes
DM II (Proximal myotonic myopathy) Neck flexor, elbow extensor, finger flexor, hip flexor Mild or inobvious Yes (Often a presenting complaint) Uncommon Uncommon
* Electrical myotonia is found in both disorders.
¶ Pain is generally not correlated with myotonia.
Δ Important contributors to pneumonia and respiratory failure.
Graphic 75472 Version 3.0