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Mean PaO2 values in various types of cyanotic heart disease

Mean PaO2 values in various types of cyanotic heart disease
Conditions Mean PaO2 (mmHg)

Room air

FiO2 = 0.21

100% oxygen

FiO2 = 1
Common mixing lesion* 42 64
HLHS 47 79
POTO 39 45
TGA 30 39
Mean PaO2 for specific cyanotic heart defects during hyperoxia test with administration of room air or 100% oxygen.
PaO2: partial pressure of oxygen; FiO2: fraction of inspired oxygen; HLHS: hypoplastic left heart syndrome; POTO: pulmonary outflow tract obstruction; TGA: transposition of the great arteries.
* Lesions include total anomalous pulmonary venous connection, tricuspid atresia with large ventricular septal defect, truncus arteriosus, double-outlet right ventricle, and single ventricle without pulmonary stenosis.
¶ Lesions include tetralogy of Fallot, tetralogy of Fallot associated with pulmonary atresia, tricuspid atresia associated with small ventricular septal defect, double-outlet right ventricle associated with pulmonary stenosis, and single ventricle associated with pulmonary stenosis.
Data from: Jones RW, Baumer JH, Joseph MC, Shinebourne EA. Arterial oxygen tension and response to oxygen breathing in differential diagnosis of congenital heart disease in infancy. Arch Dis Child 1976; 51:667.
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