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Uptodate Reference Title
Pagetic tibia
Pagetic tibia
This is a pagetic tibia. Note the thickened cortex, with cortical tunneling by pagetic osteoclasts. Lytic lesions (osteoclast resorption) coupled with blastic lesions (osteoblast bone formation) are causing this abnormal bone remodeling, resulting in deformity and structural impairment of bone. Note sparing of the fibula.